Reaction Details |
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Target | 5-hydroxytryptamine receptor 5A |
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Ligand | BDBM50005835 |
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Substrate/Competitor | n/a |
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Ki | >10000±n/a nM |
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Comments | PDSP_1788 |
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Citation | Plassat, JL; Boschert, U; Amlaiky, N; Hen, R The mouse 5HT5 receptor reveals a remarkable heterogeneity within the 5HT1D receptor family. EMBO J11:4779-86 (1992) [PubMed] |
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More Info.: | Get all data from this article |
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5-hydroxytryptamine receptor 5A |
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Name: | 5-hydroxytryptamine receptor 5A |
Synonyms: | 5-HT-5 | 5-HT-5A | 5-HT5 | 5-HT5a | 5-hydroxytryptamine receptor 5A | 5HT5A_MOUSE | 5ht5a | Htr5a | Serotonin 5a (5-HT5a) receptor | Serotonin receptor 5A |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 40749.33 |
Organism: | MOUSE |
Description: | 5-HT5 0 MOUSE::P30966 |
Residue: | 357 |
Sequence: | MDLPVNLTSFSLSTPSSLEPNRSLDTEVLRPSRPFLSAFRVLVLTLLGFLAAATFTWNLL
VLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMILLTWALSTVISLAPLLFG
WGETYSEPSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAAKFRMGSRKTNSVS
PVPEAVEVKNATQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFP
FFVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
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BDBM50005835 |
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n/a |
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Name | BDBM50005835 |
Synonyms: | (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide | 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide | 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide | 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide | 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide | CHEMBL128 | SUMATRIPTAN | Sumatran | Sumax |
Type | Small organic molecule |
Emp. Form. | C14H21N3O2S |
Mol. Mass. | 295.4 |
SMILES | CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 |
Structure |
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