Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetRenal dipeptidase
LigandBDBM81801
Substrate/Competitorn/a
Ki 3.58±n/a nM
CommentsPDSP_1111
Citation Shirley JTCheng JB Competition of leukotrienes and ICI-198,615 for [3H]LTD4 binding sites in guinea pig lung membranes suggests the involvement of two LTD4 receptor subtypes. J Pharmacol Exp Ther 258:531-6 (1991) [PubMed]
More Info.:Get all data from this article
 
Renal dipeptidase
Name:Renal dipeptidase
Synonyms:Dipeptidase 1 | Leukotriene D4 Alpha | Microsomal dipeptidase
Type:Enzyme Catalytic Domain
Mol. Mass.:44697.32
Organism:GUINEA PIG
Description:Leukotriene D4 Alpha 0 GUINEA PIG::P22412
Residue:409
Sequence:
MWTSWWLWPLVAVCAADQFRDLAVRIMQDTPVIDGHNDLPWQLLNLFNNQLQDPGANLSS
LAHTHTNIPKLKAGFVGGQFWSAYVPCDTQNRDAVKRTLEQIDVIQRMCQAYPETFACVT
SSTGIRQAFREGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYMTLTHSCNTPWADNWLV
DTGDDKAQSQGLSHFGQSVVKEMNRLGVMIDLAHVSVATMRAALKLSQAPVIFSHSSAYS
LCPHRRNVPDDVLQLVKETGSLVMVNFYNDYVSCSAKANLSQVADHLDHIKKVAGAAAVG
FGGDYDGVSRVPSGLEDVSKYPDLVAELLRRQWTEAEVRGALADNLLRVFEAVEQASNHA
QVPGEEPIPLGQLEASCRTNYGYSAAPSLHLPPGSLLASLVPLLLLSLP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM81801
n/a
NameBDBM81801
Synonyms:CAS_5283121 | LTC4 | NSC_5283121
TypeSmall organic molecule
Emp. Form.C30H47N3O9S
Mol. Mass.625.774
SMILESCCCCCC=CCC=CC=CC=CC(SCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O)C(O)CCCC(O)=O |w:5.4,8.7,10.9,12.11|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: