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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Dipeptidase 1 | ||
| Ligand | BDBM50297387 | ||
| Substrate/Competitor | n/a | ||
| Ki | 1.53±n/a nM | ||
| Comments | PDSP_1117 | ||
| Citation |  Shirley, JT; Cheng, JB Competition of leukotrienes and ICI-198,615 for [3H]LTD4 binding sites in guinea pig lung membranes suggests the involvement of two LTD4 receptor subtypes. J Pharmacol Exp Ther258:531-6 (1991) [PubMed] | ||
| More Info.: | Get all data from this article | ||
| Dipeptidase 1 | |||
| Name: | Dipeptidase 1 | ||
| Synonyms: | DPEP1 | DPEP1_PIG | Dipeptidase 1 | Leukotriene D4 Alpha | Microsomal dipeptidase | RDP | Renal dipeptidase | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 44697.32 | ||
| Organism: | GUINEA PIG | ||
| Description: | Leukotriene D4 Alpha 0 GUINEA PIG::P22412 | ||
| Residue: | 409 | ||
| Sequence: |
| ||
| BDBM50297387 | |||
| n/a | |||
| Name | BDBM50297387 | ||
| Synonyms: | (5S,6R,7E,9E,11Z,14Z)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoic acidS-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteine | (5S-(5R*,6S*(S*),7E,9E,11Z,14Z))-6-((2-Amino-2-carboxyethyl)thio)-5-hydroxy-7,9,11,14-eicosatetraenoic acid | 5S-hydroxy,6R-(S-cysteinyl),7E,9E,11Z,14Z-eicosatetraenoic acid | CHEMBL509456 | LTE4 | leukotriene E4 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H37NO5S | ||
| Mol. Mass. | 439.609 | ||
| SMILES | CCCCC\C=C/C\C=C/C=C/C=C/[C@@H](SC[C@H](N)C(O)=O)[C@@H](O)CCCC(O)=O |r| | ||
| Structure | 
| ||