| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain testis-specific protein |
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| Ligand | BDBM50365262 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Acetyl-Histone Binding Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 147±0.0 nM |
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| Comments | extracted |
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| Citation |  Bradner, JE; Gray, NS; Qi, J; McKeown, MR; Buckley, D Diazepane derivatives and uses thereof US Patent US9695172 Publication Date 7/4/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain testis-specific protein |
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| Name: | Bromodomain testis-specific protein |
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| Synonyms: | BRDT | BRDT_HUMAN | Bromodomain and extra-terminal motif (BET) | CT9 | Cancer/testis antigen 9 | RING3-like protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 107982.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502985 |
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| Residue: | 947 |
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| Sequence: | MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVK
LQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQ
ALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV
FPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSV
ALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVD
VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVT
MARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERV
KRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRL
KEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSR
EPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQ
ELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSS
DSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECIPPEGRTGVTQIGYCVQDTTSANTTL
VHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGD
SDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKA
RTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQD
KSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD
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| BDBM50365262 |
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| n/a |
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| Name | BDBM50365262 |
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| Synonyms: | (+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10124009, Compound (S)-JQ1 | US10202360, Example JQ-1 | US10308662, Compound JQ-1 | US10407441, Compound (S)-JQ1 | US10617680, Example JQ-1 | US10881668, Compound JQ1 | US10925881, Name (S)-JQ1 | US11020380, Example JQ-1 | US11078188, Example (+)-JQ1 | US11279703, TABLE 6.180 | US11427593, Compound JQ1 | US11466034, Example (+)-JQ1 | US9320741, (S)-JQ1 | US9695172, JQ1 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25ClN4O2S |
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| Mol. Mass. | 456.988 |
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| SMILES | Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| |
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| Structure | 
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