Reaction Details |
| Report a problem with these data |
Target | Pro-thyrotropin-releasing hormone |
---|
Ligand | BDBM16173 |
---|
Substrate/Competitor | n/a |
---|
Ki | >10000±n/a nM |
---|
Comments | PDSP_2650 |
---|
Citation | Garritsen, A; Ijzerman, AP; Tulp, MT; Cragoe, EJ; Soudijn, W Receptor binding profiles of amiloride analogues provide no evidence for a link between receptors and the Na+/H+ exchanger, but indicate a common structure on receptor proteins. J Recept Res11:891-907 (1991) [PubMed] Article |
---|
More Info.: | Get all data from this article |
---|
|
Pro-thyrotropin-releasing hormone |
---|
Name: | Pro-thyrotropin-releasing hormone |
Synonyms: | Prothyroliberin | TRH_RAT | Trh |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 29277.96 |
Organism: | RAT |
Description: | TRH 0 RAT::P01150 |
Residue: | 255 |
Sequence: | MPGPWLLLALALIFTLTGIPESCALPEAAQEEGAVTPDLPGLENVQVRPERRFLWKDLQR
VRGDLGAALDSWITKRQHPGKREEEEKDIEAEERGDLGEGGAWRLHKRQHPGRRANQDKY
SWADEEDSDWMPRSWLPDFFLDSWFSDVPQVKRQHPGRRSFPWMESDVTKRQHPGRRFID
PELQRSWEEKEGEGVLMPEKRQHPGKRALGHPCGPQGTCGQTGLLQLLGDLSRGQETLVK
QSPQVEPWDKEPLEE
|
|
|
BDBM16173 |
---|
n/a |
---|
Name | BDBM16173 |
Synonyms: | 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinamide;hydrochloride | 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide | Amiloride | Amipramidin | CHEMBL945 |
Type | Small organic molecule |
Emp. Form. | C6H8ClN7O |
Mol. Mass. | 229.627 |
SMILES | NC(=N)NC(=O)c1nc(Cl)c(N)nc1N |
Structure |
|