| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 4 |
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| Ligand | BDBM81855 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cell-Based Assay |
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| IC50 | >1.0e+4±n/a nM |
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| Citation |  Kuhn, CF; Bazin, M; Philippe, L; Zhang, J; Tylaska, L; Miret, J; Bauer, PH Bipiperidinyl carboxylic acid amides as potent, selective, and functionally active CCR4 antagonists. Chem Biol Drug Des70:268-72 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 4 |
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| Name: | C-C chemokine receptor type 4 |
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| Synonyms: | C-C CKR-4 | C-C chemokine receptor type 4 | C-C chemokine receptor type 4 (CCR4) | CC-CKR-4 | CCR-4 | CCR4 | CCR4_HUMAN | CD_antigen=CD194 | CMKBR4 | K5-5 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41406.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51679 |
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| Residue: | 360 |
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| Sequence: | MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNSVV
VLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVG
FYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTCYT
ERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKNKA
VKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCCLN
PIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL
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| BDBM81855 |
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| n/a |
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| Name | BDBM81855 |
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| Synonyms: | Bipiperidinyl carboxylic acid amide, 26 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H48N6O4 |
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| Mol. Mass. | 556.7399 |
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| SMILES | CCOC(=O)CCCCCNC(=O)N1CCC(CC1)N1CCCC(C1)C(=O)N1CCN(CC1)c1cccc(C)n1 |
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| Structure | 
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