| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
|---|
| Ligand | BDBM50002477 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 1800±n/a nM |
|---|
| Comments | PDSP_2195 |
|---|
| Citation |  Lin, CW; Shiosaki, K; Miller, TR; Witte, DG; Bianchi, BR; Wolfram, CA; Kopecka, H; Craig, R; Wagenaar, F; Nadzan, AM Characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, A-71623 and A-70874, that exhibit high potency and selectivity for cholecystokinin-A receptors. Mol Pharmacol39:346-51 (1991) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Gastrin/cholecystokinin type B receptor |
|---|
| Name: | Gastrin/cholecystokinin type B receptor |
|---|
| Synonyms: | CCKBR | Cholecystokinin A |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48683.10 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | Cholecystokinin A CCKBR GUINEA PIG::H0VZC5 |
|---|
| Residue: | 450 |
|---|
| Sequence: | MELLKLNRSLQGPGPGPGAPLCRPAGPLLNSSGAGNVSCETPRIRGAGTRVKSMAILFNV
TSLLSCWNKYRIIKVLGLSRRLRTVTKAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFG
TVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSG
LLMVPYPVYTAVQPVGPRVLQCVHRWPNARVRQTWSVLLLLLLFFVPGVVMAVAYGLISR
ELYLGLRFDGDADSESQSRVRGPGGLSGSAPGPAHQNGRCRPESGLSGEDSDGCYVQLPR
SRPALELSALAASTPAPGPGPRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRA
FDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARP
RPLPEEDPPTPSIASLSRLSYTTISTLGPG
|
|
|
|---|
| BDBM50002477 |
|---|
| n/a |
|---|
| Name | BDBM50002477 |
|---|
| Synonyms: | (S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-4-methylsulfanyl-butyrylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid | 3-{1-[1-butyl oxycarbonylamino-2-(1H-3-indolyl)ethylcarboxamido]-3-methylsulfanylpropylcarboxamido}-3-(1-carbamoyl-2-phenylethylcarbamoyl)propanoic acid | 3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-4-methylsulfanyl-butyrylamino}-N-(1-carbamoyl-2-phenyl-ethyl)-succinamic acid | Boc-CCK-4 | CHEMBL64605 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H44N6O8S |
|---|
| Mol. Mass. | 696.814 |
|---|
| SMILES | CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
