| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM50010301 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 0.3±n/a nM |
|---|
| Comments | PDSP_1725 |
|---|
| Citation |  Sunahara, RK; Guan, HC; O'Dowd, BF; Seeman, P; Laurier, LG; Ng, G; George, SR; Torchia, J; Van Tol, HH; Niznik, HB Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature350:614-9 (1991) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 49303.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21728 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
|
|
|
|---|
| BDBM50010301 |
|---|
| n/a |
|---|
| Name | BDBM50010301 |
|---|
| Synonyms: | 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SKF 83566) | CHEMBL324017 | SKF 83566 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H18BrNO |
|---|
| Mol. Mass. | 332.235 |
|---|
| SMILES | CN1CCc2cc(Br)c(O)cc2C(C1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
