| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1B) dopamine receptor |
|---|
| Ligand | BDBM50026957 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 7±n/a nM |
|---|
| Comments | PDSP_268 |
|---|
| Citation |  Tiberi, M; Jarvie, KR; Silvia, C; Falardeau, P; Gingrich, JA; Godinot, N; Bertrand, L; Yang-Feng, TL; Fremeau, RT; Caron, MG Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor. Proc Natl Acad Sci U S A88:7491-5 (1991) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| D(1B) dopamine receptor |
|---|
| Name: | D(1B) dopamine receptor |
|---|
| Synonyms: | D(1B) dopamine receptor | DOPAMINE D5 | DRD5_RAT | Dopamine D1B | Dopamine D5 receptor | Dopamine receptor | Drd5 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 52827.88 |
|---|
| Organism: | RAT |
|---|
| Description: | Dopamine D1B 0 RAT::P25115 |
|---|
| Residue: | 475 |
|---|
| Sequence: | MLPPGRNRTAQPARLGLQRQLAQVDAPAGSATPLGPAQVVTAGLLTLLIVWTLLGNVLVC
AAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGTFCDIWVAFDIM
CSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHR
DKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYT
RIYRIAQVQIRRISSLERAAEHAQSCRSRGAYEPDPSLRASIKKETKVFKTLSMIMGVFV
CCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIFVWFGWANSSLNPIIYAFNADF
RKVFAQLLGCSHFCFRTPVQTVNISNELISYNQDTVFHKEIATAYVHMIPNAVSSGDREV
GEEEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFDKTA
|
|
|
|---|
| BDBM50026957 |
|---|
| n/a |
|---|
| Name | BDBM50026957 |
|---|
| Synonyms: | (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol) | (trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol | 2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol | 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol | FLUPENTHIXOL, Alpha | FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol | Flupenthixol | Flupenthixol, Beta |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H25F3N2OS |
|---|
| Mol. Mass. | 434.518 |
|---|
| SMILES | OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
