| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor 3 |
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| Ligand | BDBM50002370 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_292 |
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| Citation |  Madsen, U; Ferkany, JW; Jones, BE; Ebert, B; Johansen, TN; Holm, T; Krogsgaard-Larsen, P NMDA receptor agonists derived from ibotenic acid. Preparation, neuroexcitation and neurotoxicity. Eur J Pharmacol189:381-91 (1990) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Glutamate receptor 3 |
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| Name: | Glutamate receptor 3 |
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| Synonyms: | GRIA3_RAT | Glur3 | Glutamate receptor 3 | Glutamate receptor ionotropic, AMPA 3 | Glutamate-AMPA | Gria3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 100383.57 |
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| Organism: | RAT |
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| Description: | Glutamate-AMPA GRIA3 RAT::P19492 |
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| Residue: | 888 |
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| Sequence: | MGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTE
KPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVT
PSFPTDADVQFVIQMRPALKGAILSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNW
QVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYM
LANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYT
SALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGM
TGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIV
VTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPE
TKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFS
FLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIF
NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE
SAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVR
KSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLN
EQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEF
CYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI
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| BDBM50002370 |
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| n/a |
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| Name | BDBM50002370 |
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| Synonyms: | (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-propionic acid | (RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-propionicacid | 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid | 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid(DL-AMPA) | 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)-propionic acid | 2-amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid | 2-ammonio-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoate | AMPA | CHEMBL13378 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H10N2O4 |
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| Mol. Mass. | 186.1653 |
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| SMILES | Cc1o[nH]c(=O)c1CC(N)C(O)=O |
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| Structure | 
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