| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM81889 |
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| Substrate/Competitor | n/a |
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| Ki | 8.1±n/a nM |
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| Comments | PDSP_1039 |
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| Citation |  Pettibone, DJ; Clineschmidt, BV; Lis, EV; Reiss, DR; Totaro, JA; Woyden, CJ; Bock, MG; Freidinger, RM; Tung, RD; Veber, DF In vitro pharmacological profile of a novel structural class of oxytocin antagonists. J Pharmacol Exp Ther256:304-8 (1991) [PubMed] |
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| More Info.: | Get all data from this article |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OXTR | OXYR_MACMU | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42932.85 |
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| Organism: | Rhesus |
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| Description: | Oxytocin OXTR Rhesus::P56494 |
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| Residue: | 389 |
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| Sequence: | MEGELAANWSTEAVNSSAAPPGAEGNCTAGPPRRNEALARVEVAVLCLILFLALSGNACV
LLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRMALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGNRLGET
STSKKSNSSSFVLSHRSSSQRSCSQPSTA
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| BDBM81889 |
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| n/a |
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| Name | BDBM81889 |
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| Synonyms: | Cyclo[L-Pro-D-Phe-L-Ile-1,6-didehydro-D-Pyz-5-[(dimethylamino)methyl]-L-Pyz-N-methyl-D-Phe-] | J440.775J | L-366,670 |
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| Type | Small organic molecule |
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| Emp. Form. | C43H59N9O6 |
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| Mol. Mass. | 797.9853 |
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| SMILES | CCC(C)C1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@H]2CC(CN(C)C)CNN2C(=O)[C@H]2CCC=NN2C1=O |c:57| |
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| Structure | 
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