| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM81892 |
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| Substrate/Competitor | n/a |
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| Ki | 13±n/a nM |
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| Comments | PDSP_1041 |
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| Citation |  Pettibone, DJ; Clineschmidt, BV; Lis, EV; Reiss, DR; Totaro, JA; Woyden, CJ; Bock, MG; Freidinger, RM; Tung, RD; Veber, DF In vitro pharmacological profile of a novel structural class of oxytocin antagonists. J Pharmacol Exp Ther256:304-8 (1991) [PubMed] |
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| More Info.: | Get all data from this article |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OT-R | OXYR_RAT | Otr | Oxtr | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42889.28 |
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| Organism: | RAT |
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| Description: | Oxytocin OXTR RAT::P70536 |
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| Residue: | 388 |
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| Sequence: | MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACV
LLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD
VNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETS
VSKKSNSSTFVLSRRSSSQRSCSQPSSA
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| BDBM81892 |
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| n/a |
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| Name | BDBM81892 |
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| Synonyms: | Cyclo[L-Pro-D-Phe-L-Ile-1,6-didehydro-D-Pyz-N-methyl-D-Phe-] | J440.774A | L-366,706 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H44N6O5 |
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| Mol. Mass. | 628.7611 |
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| SMILES | CCC(C)C1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]2CCCN2C(=O)C(Cc2ccccc2)N(C)C(=O)[C@H]2CCC=NN2C1=O |c:44| |
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| Structure | 
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