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TargetOxytocin receptor
LigandBDBM81891
Substrate/Competitorn/a
Ki 0.8±n/a nM
CommentsPDSP_1044
Citation Pettibone DJClineschmidt BVLis EVReiss DRTotaro JAWoyden CJBock MGFreidinger RMTung RDVeber DF In vitro pharmacological profile of a novel structural class of oxytocin antagonists. J Pharmacol Exp Ther 256:304-8 (1991) [PubMed]
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Oxytocin receptor
Name:Oxytocin receptor
Synonyms:OT-R | Oxytocin
Type:Enzyme Catalytic Domain
Mol. Mass.:42889.28
Organism:RAT
Description:Oxytocin OXTR RAT::P70536
Residue:388
Sequence:
MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACV
LLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD
VNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETS
VSKKSNSSTFVLSRRSSSQRSCSQPSSA
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  Blast E-value cutoff:
BDBM81891
n/a
NameBDBM81891
Synonyms:CAS_188397 | L-366,948 | NSC_188397
TypeSmall organic molecule
Emp. Form.C42H56N8O6
Mol. Mass.768.944
SMILESCCC(C)C(NC(=O)C(N)Cc1ccc2ccccc2c1)C(=O)C1(CCCN1C(=O)C(N)CC1=NC(N=C1)(C(=O)N1CCCCC1)C(=O)N1CCCCC1)C=O |c:39,t:36|
Structure
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