| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
|---|
| Ligand | BDBM50011875 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 80.5±n/a nM |
|---|
| Comments | PDSP_430 |
|---|
| Citation |  Tahraoui, L; Floch, A; Cavero, I Functional validation of platelet-activating factor receptor sites characterized biochemically by a specific and reproducible [3H]platelet-activating factor binding in human platelets. J Pharmacol Exp Ther252:1221-7 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Platelet-activating factor receptor |
|---|
| Name: | Platelet-activating factor receptor |
|---|
| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 39219.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
|---|
| Residue: | 342 |
|---|
| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
|
|
|
|---|
| BDBM50011875 |
|---|
| n/a |
|---|
| Name | BDBM50011875 |
|---|
| Synonyms: | 2-Bromo-4-(2-chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene | BROTIZOLAM | CHEMBL32479 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H10BrClN4S |
|---|
| Mol. Mass. | 393.689 |
|---|
| SMILES | Cc1nnc2CN=C(c3cc(Br)sc3-n12)c1ccccc1Cl |c:6| |
|---|
| Structure | 
|
|---|
Search and Browse
