| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM22417 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_1329 |
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| Citation |  Hyttel, J; Larsen, JJ Neurochemical profile of Lu 19-005, a potent inhibitor of uptake of dopamine, noradrenaline, and serotonin. J Neurochem44:1615-22 (1985) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM22417 |
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| n/a |
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| Name | BDBM22417 |
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| Synonyms: | 3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine | CHEMBL295467 | LY 135252 | LY 94939 | LY135252 | LY139602 | Nisoxetine | Nisoxetine Inhibitor | US9944618, Compound ID No. 177 | [3-(2-methoxyphenoxy)-3-phenylpropyl](methyl)amine | [3H]Nisoxetine |
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| Type | radiolabeled ligand |
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| Emp. Form. | C17H21NO2 |
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| Mol. Mass. | 271.3541 |
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| SMILES | CNCCC(Oc1ccccc1OC)c1ccccc1 |
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| Structure | 
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