| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2B adrenergic receptor |
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| Ligand | BDBM66983 |
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| Substrate/Competitor | n/a |
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| Ki | 42±n/a nM |
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| Comments | PDSP_1727 |
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| Citation |  Hieble, JP; DeMarinis, RM; Fowler, PJ; Matthews, WD Selective alpha-2 adrenoceptor blockade by SK&F 86466: in vitro characterization of receptor selectivity. J Pharmacol Exp Ther236:90-6 (1986) [PubMed] |
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| More Info.: | Get all data from this article |
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| Alpha-2B adrenergic receptor |
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| Name: | Alpha-2B adrenergic receptor |
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| Synonyms: | Alpha 2B adrenergic receptor | adrenergic Alpha2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42242.60 |
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| Organism: | Dog |
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| Description: | Q2MDQ0 |
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| Residue: | 387 |
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| Sequence: | AIAAVITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANE
LLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCII
LTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYL
RIYLIAKRSHRRGPRAAGGRGEGESKQPHSVPTAASTKLPTLASLAASGEANGHSKPTGE
KEEGDTSEDPGTPALPPSWSAVPNPGQSQKEGVCGASPEEEAEMEEGEEECEPQALPASP
AAACSPPLRQPQGSRVLATLRGQVLLGRGVGTTSGQWWRRRAQLTREKRFTFVLAVVIGV
FVLCWFPFFFSYSLGAICPQHCKVPHG
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| BDBM66983 |
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| n/a |
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| Name | BDBM66983 |
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| Synonyms: | 6-chloranyl-3-methyl-1,2,4,5-tetrahydro-3-benzazepine;hydrochloride | 6-chloro-3-methyl-1,2,4,5-tetrahydro-3-benzazepine;hydrochloride | CHEMBL123349 | MLS002172470 | SKF 86466 | SKF-86466 hydrochloride | SMR001254100 | cid_10220250 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H14ClN |
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| Mol. Mass. | 195.689 |
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| SMILES | CN1CCc2cccc(Cl)c2CC1 |
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| Structure | 
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