Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50209301 |
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Substrate/Competitor | n/a |
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Ki | 16.1±n/a nM |
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Comments | PDSP_7116 |
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Citation | Blanchard, SG; Lee, PH; Pugh, WW; Hong, JS; Chang, KJ Characterization of the binding of a morphine (mu) receptor-specific ligand: Tyr-Pro-NMePhe-D-Pro-NH2, [3H]-PL17. Mol Pharmacol31:326-33 (1987) [PubMed] |
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More Info.: | Get all data from this article |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 44503.11 |
Organism: | Rattus norvegicus (rat) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
Residue: | 398 |
Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50209301 |
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n/a |
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Name | BDBM50209301 |
Synonyms: | (S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N-((S)-1-((S)-1-amino-3-methyl-1-oxobutan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide | CHEMBL390914 | Morphiceptin [Val4] |
Type | Small organic molecule |
Emp. Form. | C28H37N5O5 |
Mol. Mass. | 523.6239 |
SMILES | CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O |
Structure |
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