| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H1 receptor |
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| Ligand | BDBM67545 |
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| Substrate/Competitor | n/a |
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| Ki | 2±n/a nM |
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| Comments | PDSP_1532 |
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| Citation |  Richelson, E; Nelson, A Antagonism by neuroleptics of neurotransmitter receptors of normal human brain in vitro. Eur J Pharmacol103:197-204 (1984) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Histamine H1 receptor |
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| Name: | Histamine H1 receptor |
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| Synonyms: | H1R | HH1R | HISTAMINE H1 | HRH1 | HRH1_HUMAN |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 55808.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Cell pellets from SK-N-MC cells transfected with human H1 receptor were used in binding assay. |
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| Residue: | 487 |
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| Sequence: | MSLPNSSCLLEDKMCEGNKTTMASPQLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHT
VGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFI
LCIDRYRSVQQPLRYLKYRTKTRASATILGAWFLSFLWVIPILGWNHFMQQTSVRREDKC
ETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINRSLPSFSEIKLR
PENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKL
YCFPLDIVHMQAAAEGSSRDYVAVNRSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSR
TDSDTTTETAPGKGKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFI
MAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFK
RILHIRS
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| BDBM67545 |
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| n/a |
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| Name | BDBM67545 |
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| Synonyms: | N,N-dimethyl-3-(10-phenothiazinyl)-1-propanamine;hydrochloride | N,N-dimethyl-3-phenothiazin-10-yl-propan-1-amine;hydrochloride | N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride | PROMAZINE | SR-01000000228-4 | US9504692, Promazine | cid_5887 | dimethyl(3-phenothiazin-10-ylpropyl)amine;hydrochloride |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20N2S |
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| Mol. Mass. | 284.419 |
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| SMILES | CN(C)CCCN1c2ccccc2Sc2ccccc12 |
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| Structure | 
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