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TargetProstanoid IP receptor
LigandBDBM50101822
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_5309
Citation Blair IAMacDermot J The binding of [3H]-prostacyclin to membranes of a neuronal somatic hybrid. Br J Pharmacol 72:435-41 (1981) [PubMed]  Article
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Prostanoid IP receptor
Name:Prostanoid IP receptor
Synonyms:PGI receptor | Prostacyclin (IP) Receptor | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Prostaglandin I2 receptor
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40968.22
Organism:Homo sapiens (Human)
Description:The membranes prepared from human platelet were used in binding assay.
Residue:386
Sequence:
MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD
LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA
LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG
GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL
LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL
PPTQQSSGSAVGTSSKAEASVACSLC
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  Blast E-value cutoff:
BDBM50101822
n/a
NameBDBM50101822
Synonyms:(Z)-7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-oct-1-enyl)-5-oxo-cyclopentyl]-hept-5-enoic acid | CHEMBL64804 | PGE2, 15-epi | US9180116, PGE2
TypeSmall organic molecule
Emp. Form.C20H32O5
Mol. Mass.352.4651
SMILESCCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
Structure
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