Reaction Details |
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Target | P2X purinoceptor 3 |
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Ligand | BDBM271612 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Rat P2X3 Binding Assay in Rat Serum Albumin (HSA) |
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IC50 | 10.00±n/a nM |
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Citation | Kai, H Aminotriazine derivative and pharmaceutical composition comprising the same US Patent US10065941 Publication Date 9/4/2018 |
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More Info.: | Get all data from this article, Assay Method |
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P2X purinoceptor 3 |
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Name: | P2X purinoceptor 3 |
Synonyms: | ATP receptor | P2RX3_RAT | P2X purinoceptor 3 | P2X3 | P2rx3 | Purinergic receptor | ratp2x3 | ratp2x3 + rsa |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 44397.63 |
Organism: | RAT |
Description: | Purinergic, P2X3 0 RAT::P49654 |
Residue: | 397 |
Sequence: | MNCISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGFGRYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPENEEKYRCVSDS
QCGPERFPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVEMPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTDKDIKRCRFHPEKAPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDGVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADHYKARKFEE
VTETTLKGTASTNPVFASDQATVEKQSTDSGAYSIGH
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BDBM271612 |
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n/a |
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Name | BDBM271612 |
Synonyms: | US10065941, Compound I-113 | US9732060, Compound I-113 |
Type | Small organic molecule |
Emp. Form. | C28H29N5O5 |
Mol. Mass. | 515.5604 |
SMILES | C[C@H]([C@H](C)n1c(=O)[nH]\c(=N/c2ccc(Oc3ccc(C)cn3)cc2)n(Cc2ccc(C)cc2)c1=O)C(O)=O |r| |
Structure |
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