| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 3 |
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| Ligand | BDBM271675 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Rat P2X3 Binding Assay in Rat Serum Albumin (HSA) |
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| IC50 | 6.00±n/a nM |
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| Citation |  Kai, H Aminotriazine derivative and pharmaceutical composition comprising the same US Patent US10065941 Publication Date 9/4/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 3 |
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| Name: | P2X purinoceptor 3 |
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| Synonyms: | ATP receptor | P2RX3_RAT | P2X purinoceptor 3 | P2X3 | P2rx3 | Purinergic receptor | ratp2x3 | ratp2x3 + rsa |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44397.63 |
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| Organism: | RAT |
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| Description: | Purinergic, P2X3 0 RAT::P49654 |
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| Residue: | 397 |
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| Sequence: | MNCISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGFGRYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPENEEKYRCVSDS
QCGPERFPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVEMPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTDKDIKRCRFHPEKAPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDGVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADHYKARKFEE
VTETTLKGTASTNPVFASDQATVEKQSTDSGAYSIGH
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| BDBM271675 |
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| n/a |
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| Name | BDBM271675 |
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| Synonyms: | US10065941, Compound R-014 | US9732060, Compound R-014 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20Cl2N6O5 |
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| Mol. Mass. | 543.359 |
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| SMILES | C[C@@H](Cn1c(=O)[nH]\c(=N/c2ccc(Oc3cnc(Cl)cn3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(O)=O |r| |
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| Structure | 
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