| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 1 |
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| Ligand | BDBM50137675 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Inhbition Assay |
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| pH | 7.5±0 |
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| Temperature | 293.15±0 K |
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| Ki | 840±0.0 nM |
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| Citation |  Winum, JY; Montero, JL; Vullo, D; Supuran, CT Carbonic anhydrase inhibitors: glycosylsulfanilamides act as subnanomolar inhibitors of the human secreted isoform VI. Chem Biol Drug Des74:636-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Carbonic anhydrase 1 |
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| Name: | Carbonic anhydrase 1 |
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| Synonyms: | CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA |
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| Type: | Enzyme |
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| Mol. Mass.: | 28873.37 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00915 |
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| Residue: | 261 |
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| Sequence: | MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
PMQHNNRPTQPLKGRTVRASF
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| BDBM50137675 |
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| n/a |
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| Name | BDBM50137675 |
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| Synonyms: | 4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-benzenesulfonamide | CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 4 | N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 5 | N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H16N2O6S |
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| Mol. Mass. | 304.32 |
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| SMILES | NS(=O)(=O)c1ccc(NC2OCC(O)C(O)C2O)cc1 |
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| Structure | 
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