| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
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| Ligand | BDBM50084033 |
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| Substrate/Competitor | n/a |
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| Ki | 0.06±n/a nM |
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| Comments | PDSP_2198 |
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| Citation |  Ito, H; Sogabe, H; Nakarai, T; Sato, Y; Tomoi, M; Kadowaki, M; Matsuo, M; Tokoro, K; Yoshida, K Pharmacological profile of FK480, a novel cholecystokinin type-A receptor antagonist: comparison to loxiglumide. J Pharmacol Exp Ther268:571-5 (1994) [PubMed] |
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| More Info.: | Get all data from this article |
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| Gastrin/cholecystokinin type B receptor |
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| Name: | Gastrin/cholecystokinin type B receptor |
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| Synonyms: | CCKBR | Cholecystokinin A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48683.10 |
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| Organism: | GUINEA PIG |
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| Description: | Cholecystokinin A CCKBR GUINEA PIG::H0VZC5 |
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| Residue: | 450 |
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| Sequence: | MELLKLNRSLQGPGPGPGAPLCRPAGPLLNSSGAGNVSCETPRIRGAGTRVKSMAILFNV
TSLLSCWNKYRIIKVLGLSRRLRTVTKAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFG
TVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSG
LLMVPYPVYTAVQPVGPRVLQCVHRWPNARVRQTWSVLLLLLLFFVPGVVMAVAYGLISR
ELYLGLRFDGDADSESQSRVRGPGGLSGSAPGPAHQNGRCRPESGLSGEDSDGCYVQLPR
SRPALELSALAASTPAPGPGPRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRA
FDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARP
RPLPEEDPPTPSIASLSRLSYTTISTLGPG
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| BDBM50084033 |
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| n/a |
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| Name | BDBM50084033 |
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| Synonyms: | 1H-Indole-2-carboxylic acid [(R)-1-(2-fluoro-phenyl)-4-oxo-3,4,6,7-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-3-yl]-amide | CHEMBL333994 | FK480 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H19FN4O2 |
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| Mol. Mass. | 438.4531 |
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| SMILES | Fc1ccccc1C1=N[C@@H](NC(=O)c2cc3ccccc3[nH]2)C(=O)N2CCc3cccc1c23 |t:8| |
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| Structure | 
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