| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nicotinic acetylcholine receptor |
|---|
| Ligand | BDBM50035398 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | >10000±n/a nM |
|---|
| Comments | PDSP_222 |
|---|
| Citation |  Arneric, SP; Sullivan, JP; Briggs, CA; Donnelly-Roberts, D; Anderson, DJ; Raszkiewicz, JL; Hughes, ML; Cadman, ED; Adams, P; Garvey, DS (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization. J Pharmacol Exp Ther270:310-8 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Nicotinic acetylcholine receptor |
|---|
| Name: | Nicotinic acetylcholine receptor |
|---|
| Synonyms: | Nicotinic acetylcholine receptor | n-AChR |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 2478.99 |
|---|
| Organism: | RAT |
|---|
| Description: | n-AChR 0 RAT::Q62594 |
|---|
| Residue: | 23 |
|---|
| Sequence: | |
|---|
| BDBM50035398 |
|---|
| n/a |
|---|
| Name | BDBM50035398 |
|---|
| Synonyms: | (S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidinium | (S)-3-methyl-5-(1-methylpyrrolidin-2-yl)isoxazole | 3-Methyl-5-((S)-1-methyl-pyrrolidin-2-yl)-isoxazole | ABT-418 | CHEMBL274525 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H14N2O |
|---|
| Mol. Mass. | 166.2203 |
|---|
| SMILES | CN1CCC[C@H]1c1cc(C)no1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
