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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histone deacetylase 9 | ||
| Ligand | BDBM272078 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | HDAC9 Biochemicle Assay | ||
| IC50 | 15.0±n/a nM | ||
| Citation |  Dominguez, C; Muñoz-Sanjuán, I; Bürli, RW; Luckhurst, CA; Allen, DR; Raphy, G; Breccia, P; Haughan, AF; Wishart, G; Hughes, SJ; Jarvis, RE; Vater, HD; Penrose, SD; Wall, M; Stott, AJ; Saville-Stones, EA Histone deacetylase inhibitors and compositions and methods of use thereof US Patent US10065948 Publication Date 9/4/2018 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Histone deacetylase 9 | |||
| Name: | Histone deacetylase 9 | ||
| Synonyms: | HD9 | HDAC7 | HDAC7B | HDAC9 | HDAC9_HUMAN | HDRP | Histone acetylase 9 (HDAC9) | Histone deacetylase 7B | Histone deacetylase 9 (HDAC9) | Histone deacetylase-related protein | Human HDAC9 | KIAA0744 | MITR | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 111304.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q9UKV0 | ||
| Residue: | 1011 | ||
| Sequence: |
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| BDBM272078 | |||
| n/a | |||
| Name | BDBM272078 | ||
| Synonyms: | (S)-1-(2-Chloro-6-fluorophenyl)-5-(3-fluoro-2- methylphenyl)-N-hydroxy-1,4,5,6- tetrahydrocyclopenta[c]pyrazole-5-carboxamide | US10065948, 14 | US10457675, Example 14 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H16ClF2N3O2 | ||
| Mol. Mass. | 403.81 | ||
| SMILES | Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1c(F)cccc1Cl)C(=O)NO |r,wD:8.8,(-.17,-3.49,;1.37,-3.49,;2.14,-4.83,;1.37,-6.16,;3.68,-4.83,;4.45,-3.49,;3.68,-2.16,;2.14,-2.16,;1.37,-.83,;.12,-1.73,;-1.13,-.83,;-2.67,-.83,;-3.14,.64,;-1.9,1.54,;-.65,.64,;.89,.64,;-1.9,3.08,;-.56,3.85,;.77,3.08,;-.56,5.39,;-1.9,6.16,;-3.23,5.39,;-3.23,3.85,;-4.56,3.08,;2.77,-.2,;4.02,-1.11,;2.93,1.33,;4.56,2.27,)| | ||
| Structure | 
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