Reaction Details | |||
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Target | Type-2 angiotensin II receptor | ||
Ligand | BDBM82260 | ||
Substrate/Competitor | n/a | ||
Ki | 1.3±n/a nM | ||
Comments | PDSP_1938 | ||
Citation | Kushida, H; Nomura, S; Morita, O; Harasawa, Y; Suzuki, M; Nakano, M; Ozawa, K; Kunihara, M Pharmacological characterization of the nonpeptide angiotensin II receptor antagonist, U-97018. J Pharmacol Exp Ther274:1042-53 (1995) [PubMed] | ||
More Info.: | Get all data from this article | ||
Type-2 angiotensin II receptor | |||
Name: | Type-2 angiotensin II receptor | ||
Synonyms: | AGTR2_RAT | AT2 | Agtr2 | Angiotensin II AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Type-2 angiotensin II receptor | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 41346.62 | ||
Organism: | RAT | ||
Description: | Angiotensin II AT2 0 0::P35351 | ||
Residue: | 363 | ||
Sequence: |
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BDBM82260 | |||
n/a | |||
Name | BDBM82260 | ||
Synonyms: | U-97018 | ||
Type | Small organic molecule | ||
Emp. Form. | C29H32N8O | ||
Mol. Mass. | 508.6174 | ||
SMILES | [H]C12CCC([H])(CC1)N1N2Cc2nc(CCCC)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c2C1=O |TLB:38:8:2.3:7.6,THB:10:9:2.3:7.6,(17.17,4.69,;16.48,6.31,;19.3,5.14,;18.9,3.65,;16.08,4.82,;17.54,5.9,;14.57,7.62,;15.91,8.39,;13.41,3.28,;12.64,4.62,;11.04,4.64,;10.22,3.26,;8.67,2.92,;8.5,1.34,;7.17,.57,;5.83,1.34,;4.5,.57,;3.17,1.34,;9.96,.69,;10.27,-.82,;9.13,-1.85,;7.66,-1.37,;6.52,-2.4,;6.84,-3.91,;8.3,-4.38,;9.45,-3.36,;5.69,-4.93,;4.23,-4.46,;3.08,-5.48,;3.4,-6.99,;4.86,-7.47,;6.01,-6.44,;7.47,-6.92,;7.94,-8.38,;9.48,-8.39,;9.96,-6.92,;8.72,-6.02,;11.03,1.87,;12.63,1.88,;13.42,.56,)| | ||
Structure |