| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 5A |
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| Ligand | BDBM21393 |
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| Substrate/Competitor | n/a |
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| Ki | 1000±n/a nM |
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| Comments | PDSP_205 |
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| Citation |  Erlander, MG; Lovenberg, TW; Baron, BM; de Lecea, L; Danielson, PE; Racke, M; Slone, AL; Siegel, BW; Foye, PE; Cannon, K Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain. Proc Natl Acad Sci U S A90:3452-6 (1993) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 5A |
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| Name: | 5-hydroxytryptamine receptor 5A |
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| Synonyms: | 5-HT-5A | 5-HT5a | 5-hydroxytryptamine receptor 5A | 5HT5A_RAT | 5ht5a | Htr5a | REC17 | Serotonin (5-HT) receptor | Serotonin receptor 5A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40684.21 |
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| Organism: | RAT |
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| Description: | 5-HT5a HTR5A RAT::P35364 |
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| Residue: | 357 |
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| Sequence: | MDLPINLTSFSLSTPSTLEPNRSLDTEALRTSQSFLSAFRVLVLTLLGFLAAATFTWNLL
VLATILRVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRARKRVSNVMILLTWALSAVISLAPLLFG
WGETYSELSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYKAAKFRMGSRKTNSVS
PIPEAVEVKDASQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFP
FFVTELISPLCSWDIPALWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
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| BDBM21393 |
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| n/a |
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| Name | BDBM21393 |
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| Synonyms: | 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-OH-DPAT | 8-OH-DPAT,(+) | 8-OH-DPAT,(-) | 8-hydroxy-N,N-dipropylaminotetralin | CHEMBL1788118 | CHEMBL505765 | CHEMBL56 | DPAT | US10562853, Compound 8-OH-DPAT | [3H]-8-OH-DPAT | cid_1220 |
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| Type | radiolabeled ligand |
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| Emp. Form. | C16H25NO |
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| Mol. Mass. | 247.3758 |
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| SMILES | CCCN(CCC)C1CCc2cccc(O)c2C1 |
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| Structure | 
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