| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 5B |
|---|
| Ligand | BDBM28582 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 1000±n/a nM |
|---|
| Comments | PDSP_719 |
|---|
| Citation |  Erlander, MG; Lovenberg, TW; Baron, BM; de Lecea, L; Danielson, PE; Racke, M; Slone, AL; Siegel, BW; Foye, PE; Cannon, K Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain. Proc Natl Acad Sci U S A90:3452-6 (1993) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| 5-hydroxytryptamine receptor 5B |
|---|
| Name: | 5-hydroxytryptamine receptor 5B |
|---|
| Synonyms: | 5-HT5B | 5-hydroxytryptamine receptor 5B | 5HT5B_RAT | 5ht5b | Htr5b | Serotonin (5-HT) receptor | Serotonin 5b (5-HT5b) receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 41141.95 |
|---|
| Organism: | RAT |
|---|
| Description: | 5-HT5B 0 RAT::P35365 |
|---|
| Residue: | 370 |
|---|
| Sequence: | MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGREPPFSAFTVLVVTLLV
LLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRW
QLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRRRASALMIAITWA
LSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYVPLAVVLFVYWKIYKAA
KFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCRATVAFQTSGDSWREQKEKRAAMMV
GILIGVFVLCWIPFFLTELVSPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNN
AFKSLFTKQR
|
|
|
|---|
| BDBM28582 |
|---|
| n/a |
|---|
| Name | BDBM28582 |
|---|
| Synonyms: | 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | CHEMBL6616 | DOI | DOI,(+) | DOI,(-) | [125I]2,5-dimethoxy-4-iodoamphetamine | [125I]4-iodo-2,5-dimethoxyphenylisopropylamine | [125I]DOI |
|---|
| Type | radiolabeled ligand |
|---|
| Emp. Form. | C11H16INO2 |
|---|
| Mol. Mass. | 321.1547 |
|---|
| SMILES | COc1cc(CC(C)N)c(OC)cc1I |
|---|
| Structure | 
|
|---|
Search and Browse
