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Target5-HT5B
LigandBDBM35234
Substrate/Competitorn/a
Ki 1000±n/a nM
CommentsPDSP_1348
Citation Erlander MGLovenberg TWBaron BMde Lecea LDanielson PERacke MSlone ALSiegel BWFoye PECannon K Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain. Proc Natl Acad Sci U S A 90:3452-6 (1993) [PubMed]
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5-HT5B
Name:Serotonin (5-HT) receptor
Synonyms:5-hydroxytryptamine receptor 5B | Serotonin 5b (5-HT5b) receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:41141.95
Organism:RAT
Description:5-HT5B 0 RAT::P35365
Residue:370
Sequence:
MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGREPPFSAFTVLVVTLLV
LLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRW
QLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRRRASALMIAITWA
LSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYVPLAVVLFVYWKIYKAA
KFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCRATVAFQTSGDSWREQKEKRAAMMV
GILIGVFVLCWIPFFLTELVSPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNN
AFKSLFTKQR
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BDBM35234
n/a
NameBDBM35234
Synonyms:DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradrenaline,(+) | [3H]NE
Typeradiolabeled ligand
Emp. Form.C8H11NO3
Mol. Mass.169.1778
SMILESNCC(O)c1ccc(O)c(O)c1
Structure
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