| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glutamate metabotropic receptor 1 |
|---|
| Ligand | BDBM50004863 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 9300±n/a nM |
|---|
| Comments | PDSP_96 |
|---|
| Citation |  Joly, C; Gomeza, J; Brabet, I; Curry, K; Bockaert, J; Pin, JP Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1. J Neurosci15:3970-81 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Glutamate metabotropic receptor 1 |
|---|
| Name: | Glutamate metabotropic receptor 1 |
|---|
| Synonyms: | Metabotropic Glutamate 1a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 101383.99 |
|---|
| Organism: | PORCINE |
|---|
| Description: | F1S737 |
|---|
| Residue: | 906 |
|---|
| Sequence: | MVRLLLLFFPAVFLEMSLFPRGPGGKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAE
KVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSI
EFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDI
PQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESG
MDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLL
SAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLD
TNTRNPWFPEFWQHRFQCRLPGHILENPNFKRICTGNESLEENYVQDSKMGFVINAIYAM
AHGLQNMHHALCPGHVGLCDAMKPIDGSKLLDFLIKSTFIGVSGEEVWFDEKGDAPGRYD
IMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGVVRSVCSEPCLKGQIKVIRKGE
VSCCWICTACKENEYVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFS
CLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQ
RLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTL
VVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPAN
FNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIA
KPERNVRSAFTTSDVVRMHVGDGKLPCRSNTFLNIFRRKKPGAGNAKKRQPEFSPTSQCP
SAHVQL
|
|
|
|---|
| BDBM50004863 |
|---|
| n/a |
|---|
| Name | BDBM50004863 |
|---|
| Synonyms: | (+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,3-dicarboxylic acid | (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid | 1-Amino-cyclopentane-1,3-dicarboxylic acid (APCD) | 1-Amino-cyclopentane-1,3-dicarboxylic acid(cis-(1S,3S)-ACPD) | 1R,3R-ACPD | 1R,3S-ACPD | 1S, 3R-ACPD | CHEMBL29726 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H11NO4 |
|---|
| Mol. Mass. | 173.1665 |
|---|
| SMILES | N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
