| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M4 |
|---|
| Ligand | BDBM50064176 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 13.80±n/a nM |
|---|
| Comments | PDSP_1220 |
|---|
| Citation |  Lazareno, S; Buckley, NJ; Roberts, FF Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Mol Pharmacol38:805-15 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Muscarinic acetylcholine receptor M4 |
|---|
| Name: | Muscarinic acetylcholine receptor M4 |
|---|
| Synonyms: | ACM4_CHICK | CHRM4 | Cholinergic, muscarinic M4 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 54968.10 |
|---|
| Organism: | Chick |
|---|
| Description: | Cholinergic, muscarinic M4 CHRM4 Chick::P17200 |
|---|
| Residue: | 490 |
|---|
| Sequence: | MHNLSAQPWQAKMANLTYDNVTLSNRSEVAIQPPTNYKTVELVFIATVTGSLSLVTVVGN
ILVMLSIKVNRQLQTVNNYFLFSLACADLIIGVFSMNLYTVYIIKGYWPLGAVVCDLWLA
LDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWILSFILWAPAILF
WQFIVGKRTVHERECYIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVRRHK
PESRKERKGKSLSFFKAPPVKQNNNNSPKRAVEVKEEVRNGKVDDQPSAQTEATGQQEEK
ETSNESSTVSMTQTTKDKPTTEILPAGQGQSPAHPRVNPTSKWSKIKIVTKQTGTESVTA
IEIVPAKAGASDHNSLSNSRPANVARKFASIARSQVRKKRQMAAREKKVTRTIFAILLAF
ILTWTPYNVMVLINTFCETCVPETVWSIGYWLCYVNSTINPACYALCNATFKKTFKHLLM
CQYRNIGTAR
|
|
|
|---|
| BDBM50064176 |
|---|
| n/a |
|---|
| Name | BDBM50064176 |
|---|
| Synonyms: | CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''-Bis-[6-(2-methoxy-benzylamino)-hexyl]-octane-1,8-diamine | N1,N8-bis(6-(2-methoxybenzylamino)hexyl)octane-1,8-diamine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C36H62N4O2 |
|---|
| Mol. Mass. | 582.9031 |
|---|
| SMILES | COc1ccccc1CNCCCCCCNCCCCCCCCNCCCCCCNCc1ccccc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
