| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
|---|
| Ligand | BDBM50005836 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 122±n/a nM |
|---|
| Comments | PDSP_530 |
|---|
| Citation |  Gerald, C; Adham, N; Kao, HT; Olsen, MA; Laz, TM; Schechter, LE; Bard, JA; Vaysse, PJ; Hartig, PR; Branchek, TA The 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variants. EMBO J14:2806-15 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| 5-hydroxytryptamine receptor 4 |
|---|
| Name: | 5-hydroxytryptamine receptor 4 |
|---|
| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46117.31 |
|---|
| Organism: | RAT |
|---|
| Description: | 5-HT4 HTR4 RAT::Q62758 |
|---|
| Residue: | 406 |
|---|
| Sequence: | MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSN
STFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRP
QTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRD
TVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
|
|
|
|---|
| BDBM50005836 |
|---|
| n/a |
|---|
| Name | BDBM50005836 |
|---|
| Synonyms: | 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide | 4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide | CHEMBL560739 | CISAPRIDE | PROPULSID | US10167299, Cisapride | US10800776, Example Cisapride | US9221790, Cisapride | cid_5311047 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H29ClFN3O4 |
|---|
| Mol. Mass. | 465.945 |
|---|
| SMILES | COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
