| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
|---|
| Ligand | BDBM82424 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 501.18±n/a nM |
|---|
| Comments | PDSP_1319 |
|---|
| Citation |  Schwinn, DA; Johnston, GI; Page, SO; Mosley, MJ; Wilson, KH; Worman, NP; Campbell, S; Fidock, MD; Furness, LM; Parry-Smith, DJ Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. J Pharmacol Exp Ther272:134-42 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Alpha-1B adrenergic receptor |
|---|
| Name: | Alpha-1B adrenergic receptor |
|---|
| Synonyms: | ADA1B_MESAU | ADRA1B | adrenergic Alpha1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 56514.13 |
|---|
| Organism: | HAMSTER |
|---|
| Description: | adrenergic Alpha1 0 HAMSTER::P18841 |
|---|
| Residue: | 515 |
|---|
| Sequence: | MNPDLDTGHNTSAPAQWGELKDANFTGPNQTSSNSTLPQLDVTRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSATLEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFM
RILGCQCRSGRRRRRRRRLGACAYTYRPWTRGGSLERSQSRKDSLDDSGSCMSGSQRTLP
SASPSPGYLGRGAQPPLELCAYPEWKSGALLSLPEPPGRRGRLDSGPLFTFKLLGEPESP
GTEGDASNGGCDATTDLANGQPGFKSNMPLAPGHF
|
|
|
|---|
| BDBM82424 |
|---|
| n/a |
|---|
| Name | BDBM82424 |
|---|
| Synonyms: | CAS_1236 | NSC_1236 | Niguldipine(+) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C36H39N3O6 |
|---|
| Mol. Mass. | 609.7114 |
|---|
| SMILES | COC(=O)C1C(C(C(=O)OCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O |c:36,t:33| |
|---|
| Structure | 
|
|---|
Search and Browse
