| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 1 |
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| Ligand | BDBM50033312 |
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| Substrate/Competitor | n/a |
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| Ki | 1.99±n/a nM |
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| Comments | PDSP_181 |
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| Citation |  Schwinn, DA; Johnston, GI; Page, SO; Mosley, MJ; Wilson, KH; Worman, NP; Campbell, S; Fidock, MD; Furness, LM; Parry-Smith, DJ Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. J Pharmacol Exp Ther272:134-42 (1995) [PubMed] |
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| More Info.: | Get all data from this article |
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| Solute carrier family 22 member 1 |
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| Name: | Solute carrier family 22 member 1 |
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| Synonyms: | OCT1 | S22A1_BOVIN | SLC22A1 | adrenergic Alpha1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 62499.05 |
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| Organism: | BOVINE |
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| Description: | adrenergic Alpha1 0 BOVINE::A7MBE0 |
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| Residue: | 563 |
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| Sequence: | MLTVDDVLEQVGEFGWFQKQTFLILCLLSAAFAPIYVGIVFLAFTPDHRCRSPGVAELSR
RCGWSLAEELNYTVPGPGPESQCLRYEVDWNQSTLGCLDPLASLATNGSPLPLGPCEQGW
VYDTPGSSIVTEFNLVCDDSWKVDLFQSCVNLGFFLGSLGVGYIADRFGRKVCLLATTLT
CASLGVLTAVAPDYTSLLIFRLLQGLVSKGSWTAGYTLITEFVGLGYRRTVAILYQMAFT
VGLVLLSGLAYILPHWRWLQLAVSLPIFLLLFRFWFVPESPRWLLSQKRNTEAIKIMDHI
AQKNGKLPPADLKMLSLEEDVTEKLSPSFIDLFRTPNLRKYTFILMYLWFTSSVVYQGLI
MHVGATGGNLYLDFLYSALVEFPAGFIILVTIDRFGRRYPLATSNLAAGLACFLMIFIPH
DLPWLNIMVACVGRMGITIVFQMVCLVNAELFPTFIRNLGMMVCSSLCDLGGVLTPFLVF
RLMEVWQGSPLILFAALGLVAGGMTLLLPETKGVTLPETIEDAENLQRKAKPKENKIYLQ
VQTSELNTQAAERDASQGTAQQK
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| BDBM50033312 |
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| n/a |
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| Name | BDBM50033312 |
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| Synonyms: | Benzyl-(6-chloro-2-imidazol-1-yl-quinazolin-4-yl)-amine; dihydrochloride | CHEMBL539806 | Urapidil-5-methyl |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14ClN5 |
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| Mol. Mass. | 335.79 |
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| SMILES | Clc1ccc2nc(nc(NCc3ccccc3)c2c1)-n1ccnc1 |
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| Structure | 
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