| Reaction Details |
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 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
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| Ligand | BDBM82259 |
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| Substrate/Competitor | n/a |
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| Ki | 11.7±n/a nM |
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| Comments | PDSP_1019 |
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| Citation |  Beauchamp, HT; Chang, RS; Siegl, PK; Gibson, RE In vivo receptor occupancy of the angiotensin II receptor by nonpeptide antagonists: relationship to in vitro affinities and in vivo pharmacologic potency. J Pharmacol Exp Ther272:612-8 (1995) [PubMed] |
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| More Info.: | Get all data from this article |
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| Type-2 angiotensin II receptor |
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| Name: | Type-2 angiotensin II receptor |
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| Synonyms: | AGTR2_RAT | AT2 | Agtr2 | Angiotensin II AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Type-2 angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41346.62 |
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| Organism: | RAT |
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| Description: | Angiotensin II AT2 0 0::P35351 |
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| Residue: | 363 |
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| Sequence: | MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFA
VNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDT
FVS
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| BDBM82259 |
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| n/a |
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| Name | BDBM82259 |
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| Synonyms: | CAS_123856 | L-158,809 | NSC_123856 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21N7 |
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| Mol. Mass. | 395.4597 |
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| SMILES | CCc1nc2c(C)cc(C)nc2n1-c1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |
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| Structure | 
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