| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
|---|
| Ligand | BDBM50042746 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 0.8±n/a nM |
|---|
| Comments | PDSP_1022 |
|---|
| Citation |  Beauchamp, HT; Chang, RS; Siegl, PK; Gibson, RE In vivo receptor occupancy of the angiotensin II receptor by nonpeptide antagonists: relationship to in vitro affinities and in vivo pharmacologic potency. J Pharmacol Exp Ther272:612-8 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Type-2 angiotensin II receptor |
|---|
| Name: | Type-2 angiotensin II receptor |
|---|
| Synonyms: | AGTR2_RAT | AT2 | Agtr2 | Angiotensin II AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Type-2 angiotensin II receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 41346.62 |
|---|
| Organism: | RAT |
|---|
| Description: | Angiotensin II AT2 0 0::P35351 |
|---|
| Residue: | 363 |
|---|
| Sequence: | MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFA
VNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDT
FVS
|
|
|
|---|
| BDBM50042746 |
|---|
| n/a |
|---|
| Name | BDBM50042746 |
|---|
| Synonyms: | CHEMBL122212 | L-159,882 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-phenyl-acetic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H37N3O3 |
|---|
| Mol. Mass. | 499.6438 |
|---|
| SMILES | CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
