| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM50019443 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 1.14±n/a nM |
|---|
| Comments | PDSP_1495 |
|---|
| Citation |  Fraundorfer, PF; Fertel, RH; Miller, DD; Feller, DR Biochemical and pharmacological characterization of high-affinity trimetoquinol analogs on guinea pig and human beta adrenergic receptor subtypes: evidence for partial agonism. J Pharmacol Exp Ther270:665-74 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2_CAVPO | Adrb2 | adrenergic Beta2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46993.24 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4 |
|---|
| Residue: | 418 |
|---|
| Sequence: | MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKD
AINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRF
HTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNG
KTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
|
|
|
|---|
| BDBM50019443 |
|---|
| n/a |
|---|
| Name | BDBM50019443 |
|---|
| Synonyms: | 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol | 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol((-)-Pindolol) | 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol(pindolol) | 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol | LB-46 | PINDOLOL | PINDOLOL,(-) | PRINODOLOL | VISKAZIDE | VISKEN |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H20N2O2 |
|---|
| Mol. Mass. | 248.3208 |
|---|
| SMILES | CC(C)NCC(O)COc1cccc2[nH]ccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
