| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 5B |
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| Ligand | BDBM50027065 |
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| Substrate/Competitor | n/a |
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| Ki | 15.84±n/a nM |
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| Comments | PDSP_797 |
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| Citation |  Boess, FG; Martin, IL Molecular biology of 5-HT receptors. Neuropharmacology33:275-317 (1994) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 5B |
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| Name: | 5-hydroxytryptamine receptor 5B |
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| Synonyms: | 5-HT5B | 5-hydroxytryptamine receptor 5B | 5HT5B_RAT | 5ht5b | Htr5b | Serotonin (5-HT) receptor | Serotonin 5b (5-HT5b) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41141.95 |
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| Organism: | RAT |
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| Description: | 5-HT5B 0 RAT::P35365 |
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| Residue: | 370 |
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| Sequence: | MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGREPPFSAFTVLVVTLLV
LLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRW
QLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRRRASALMIAITWA
LSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYVPLAVVLFVYWKIYKAA
KFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCRATVAFQTSGDSWREQKEKRAAMMV
GILIGVFVLCWIPFFLTELVSPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNN
AFKSLFTKQR
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| BDBM50027065 |
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| n/a |
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| Name | BDBM50027065 |
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| Synonyms: | (5'alpha)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione | (5'alpha)-5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxoergotaman | 12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergotaman-3',6',18-trione | ERGOTAMINE | Ergotamin |
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| Type | Small organic molecule |
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| Emp. Form. | C33H35N5O5 |
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| Mol. Mass. | 581.6615 |
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| SMILES | CN1C[C@@H](C=C2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N[C@]1(C)O[C@@]2(O)[C@@H]3CCCN3C(=O)[C@H](Cc3ccccc3)N2C1=O |r,c:4| |
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| Structure | 
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