| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM78940 |
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| Substrate/Competitor | n/a |
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| Ki | 0.38±n/a nM |
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| Comments | PDSP_1219 |
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| Citation |  Boess, FG; Martin, IL Molecular biology of 5-HT receptors. Neuropharmacology33:275-317 (1994) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 | 5HT6R_RAT | Htr6 | ST-B17 | Serotonin (5-HT) receptor | Serotonin 6 (5-HT6) receptor | Serotonin receptor 6 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46945.51 |
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| Organism: | RAT |
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| Description: | 5-HT6 HTR6 RAT::P31388 |
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| Residue: | 436 |
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| Sequence: | MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIVLICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTPAPGQC
RLLASLPFVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTAGQALETLQVP
RTPRPGMESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIAQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCVHCPPEHRPALPPPPCGPLTAVP
DQASACSRCCLCLCRQTQIQTPLQGAPRACSSQPSFCCLERPPGTPRHPPGPPLWSTSLS
QTLWSLRYGRIHSVPP
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| BDBM78940 |
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| n/a |
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| Name | BDBM78940 |
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| Synonyms: | METHIOTHEPIN | MLS000859918 | Methiothepin mesylate salt | SMR000326779 | cid_3039995 | mesylic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine | methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine | methanesulfonic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2S2 |
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| Mol. Mass. | 356.548 |
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| SMILES | CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1 |
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| Structure | 
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