Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
Target5-hydroxytryptamine receptor 5B
LigandBDBM55121
Substrate/Competitorn/a
Ki 1000±n/a nM
CommentsPDSP_728
Citation Wisden, WParker, EMMahle, CDGrisel, DANowak, HPYocca, FDFelder, CCSeeburg, PHVoigt, MM Cloning and characterization of the rat 5-HT5B receptor. Evidence that the 5-HT5B receptor couples to a G protein in mammalian cell membranes. FEBS Lett333:25-31 (1993) [PubMed]  Article
More Info.:Get all data from this article
 
5-hydroxytryptamine receptor 5B
Name:5-hydroxytryptamine receptor 5B
Synonyms:5-HT5B | 5-hydroxytryptamine receptor 5B | 5HT5B_RAT | 5ht5b | Htr5b | Serotonin (5-HT) receptor | Serotonin 5b (5-HT5b) receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:41141.95
Organism:RAT
Description:5-HT5B 0 RAT::P35365
Residue:370
Sequence:
MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGREPPFSAFTVLVVTLLV
LLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRW
QLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRRRASALMIAITWA
LSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYVPLAVVLFVYWKIYKAA
KFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCRATVAFQTSGDSWREQKEKRAAMMV
GILIGVFVLCWIPFFLTELVSPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNN
AFKSLFTKQR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM55121
n/a
NameBDBM55121
Synonyms:3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride | 4-(2-aminoethyl)pyrocatechol;hydrochloride | 4-(2-azanylethyl)benzene-1,2-diol;hydrochloride | Dopamine | MLS000069419 | SMR000059081 | cid_65340
TypeSmall organic molecule
Emp. Form.C8H11NO2
Mol. Mass.153.1784
SMILESNCCc1ccc(O)c(O)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: