| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 5B |
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| Ligand | BDBM50005835 |
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| Substrate/Competitor | n/a |
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| Ki | 807±n/a nM |
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| Comments | PDSP_1788 |
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| Citation |  Wisden, W; Parker, EM; Mahle, CD; Grisel, DA; Nowak, HP; Yocca, FD; Felder, CC; Seeburg, PH; Voigt, MM Cloning and characterization of the rat 5-HT5B receptor. Evidence that the 5-HT5B receptor couples to a G protein in mammalian cell membranes. FEBS Lett333:25-31 (1993) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 5B |
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| Name: | 5-hydroxytryptamine receptor 5B |
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| Synonyms: | 5-HT5B | 5-hydroxytryptamine receptor 5B | 5HT5B_RAT | 5ht5b | Htr5b | Serotonin (5-HT) receptor | Serotonin 5b (5-HT5b) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41141.95 |
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| Organism: | RAT |
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| Description: | 5-HT5B 0 RAT::P35365 |
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| Residue: | 370 |
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| Sequence: | MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGREPPFSAFTVLVVTLLV
LLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRW
QLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRRRASALMIAITWA
LSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYVPLAVVLFVYWKIYKAA
KFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCRATVAFQTSGDSWREQKEKRAAMMV
GILIGVFVLCWIPFFLTELVSPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNN
AFKSLFTKQR
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| BDBM50005835 |
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| n/a |
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| Name | BDBM50005835 |
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| Synonyms: | (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide | 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide | 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide | 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide | 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide | CHEMBL128 | SUMATRIPTAN | Sumatran | Sumax |
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| Type | Small organic molecule |
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| Emp. Form. | C14H21N3O2S |
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| Mol. Mass. | 295.4 |
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| SMILES | CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 |
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| Structure | 
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