Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetHTR3A
LigandBDBM50007872
Substrate/Competitorn/a
Ki 0.72±n/a nM
CommentsPDSP_399
Citation Bonhaus DWLoury DNJakeman LBTo ZDeSouza AEglen RMWong EH [3H]BIMU-1, a 5-hydroxytryptamine3 receptor ligand in NG-108 cells, selectively labels sigma-2 binding sites in guinea pig hippocampus. J Pharmacol Exp Ther 267:961-70 (1993) [PubMed]  Article
More Info.:Get all data from this article
 
HTR3A
Name:HTR3A
Synonyms:5-HT3 | 5-hydroxytryptamine receptor 3A | Serotonin 3a (5-HT3a) receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:55657.07
Organism:GUINEA PIG
Description:5-HT3 HTR3A GUINEA PIG::O70212
Residue:490
Sequence:
MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDW
RKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSI
WVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTF
TSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKF
YVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDT
LPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGL
LCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPP
REASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITL
VTLWSVWHYA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50007872
n/a
NameBDBM50007872
Synonyms:3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride | BIMU 1 | CHEMBL544755 | CHEMBL62023
TypeSmall organic molecule
Emp. Form.C18H24N4O2
Mol. Mass.328.4088
SMILESCCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:12:13:20:16.17|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: