BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
LigandBDBM39914
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay
IC50 15302±2558 nM
Citation PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,  Assay Method
 
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Name:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Synonyms:CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1
Type:Enzyme Catalytic Domain
Mol. Mass.:29199.89
Organism:Homo sapiens (Human)
Description:gi_10864009
Residue:261
Sequence:
MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGA
PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEI
DGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRES
CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF
FEQLSRVDDVYSVLRQPRPGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM39914
n/a
NameBDBM39914
Synonyms:2-(4-chloro-2-methyl-phenoxy)acetic acid [2-(dimethylamino)-2-keto-1-methyl-ethyl] ester | 2-(4-chloro-2-methylphenoxy)acetic acid [1-(dimethylamino)-1-oxopropan-2-yl] ester | MLS000071533 | SMR000039312 | [1-(dimethylamino)-1-oxidanylidene-propan-2-yl] 2-(4-chloranyl-2-methyl-phenoxy)ethanoate | [1-(dimethylamino)-1-oxopropan-2-yl] 2-(4-chloro-2-methylphenoxy)acetate | cid_658406
TypeSmall organic molecule
Emp. Form.C14H18ClNO4
Mol. Mass.299.75
SMILESCC(OC(=O)COc1ccc(Cl)cc1C)C(=O)N(C)C
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: