Ki Summary

Reaction Details

Report a problem with these data

Target

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Ligand

BDBM82792

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay

IC50

1779±75 nM

Citation

PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Assay Method

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Name:

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

29199.89

Organism:

Homo sapiens (Human)

Description:

gi_10864009

Residue:

261

Sequence:

MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGA
PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEI
DGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRES
CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF
FEQLSRVDDVYSVLRQPRPGS

BDBM82792

n/a

Name

BDBM82792

Synonyms:

2-[4-[(Z)-2-(2,4-diketo-5-nitro-1H-pyrimidin-6-yl)vinyl]phenoxy]-N-(m-tolyl)acetamide | MLS000690435 | N-(3-methylphenyl)-2-[4-[(Z)-2-(5-nitro-2,4-dioxo-1H-pyrimidin-6-yl)ethenyl]phenoxy]acetamide | N-(3-methylphenyl)-2-[4-[(Z)-2-[5-nitro-2,4-bis(oxidanylidene)-1H-pyrimidin-6-yl]ethenyl]phenoxy]ethanamide | N-(3-methylphenyl)-2-{4-[2-(5-nitro-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinyl)vinyl]phenoxy}acetamide | SMR000300238 | cid_5739979

Type

Small organic molecule

Emp. Form.

C21H18N4O6

Mol. Mass.

422.3908

SMILES

Cc1cccc(NC(=O)COc2ccc(C=Cc3[nH]c(=O)[nH]c(=O)c3[N+]([O-])=O)cc2)c1 |w:16.16|

Structure