Ki Summary

Reaction Details

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Target

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Ligand

BDBM83186

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay

IC50

1818±111 nM

Citation

PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Assay Method

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Name:

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

29199.89

Organism:

Homo sapiens (Human)

Description:

gi_10864009

Residue:

261

Sequence:

MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGA
PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEI
DGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRES
CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF
FEQLSRVDDVYSVLRQPRPGS

BDBM83186

n/a

Name

BDBM83186

Synonyms:

5-bromo-2-thiophenecarboxylic acid [4-[(Z)-2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]phenyl] ester | 5-bromothiophene-2-carboxylic acid [4-[(Z)-2-(1H-benzimidazol-2-yl)-2-cyano-vinyl]phenyl] ester | MLS002637278 | SMR001544644 | [4-[(Z)-2-(1H-benzimidazol-2-yl)-2-cyano-ethenyl]phenyl] 5-bromanylthiophene-2-carboxylate | [4-[(Z)-2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]phenyl] 5-bromothiophene-2-carboxylate | cid_44825356

Type

Small organic molecule

Emp. Form.

C21H12BrN3O2S

Mol. Mass.

450.308

SMILES

Brc1ccc(s1)C(=O)Oc1ccc(\C=C(\C#N)c2nc3ccccc3[nH]2)cc1

Structure