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TargetToll-like receptor 9 (TLR9)
LigandBDBM51902
Substrate/Competitorn/a
Meas. Tech.Fluorescence-based cell-based high throughput dose response assay for inhibitors of TLR9-MyD88 binding
IC50 5116±n/a nM
Citation PubChem PC Fluorescence-based cell-based high throughput dose response assay for inhibitors of TLR9-MyD88 binding PubChem Bioassay (2011)[AID]  Article
More Info.:Get all data from this article,  Assay Method
 
Toll-like receptor 9 (TLR9)
Name:Toll-like receptor 9 (TLR9)
Synonyms:Toll-like receptor 9
Type:Enzyme
Mol. Mass.:115889.91
Organism:Homo sapiens (Human)
Description:Q9NR96
Residue:1032
Sequence:
MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAA
PRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFL
AVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYY
KNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDL
ANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLN
ASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSF
GSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYV
DLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLS
RNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHS
FTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSL
RALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRL
RDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGF
FSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAA
VPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCG
WDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRG
RWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLE
DRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHF
YNRNFCQGPTAE
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  Blast E-value cutoff:
BDBM51902
n/a
NameBDBM51902
Synonyms:MLS001203758 | N-(4-Fluoro-benzylidene)-N'-(6-methoxy-2-methyl-quinolin-4-yl)-hydrazine | N-[(4-fluorophenyl)methylideneamino]-6-methoxy-2-methyl-4-quinolinamine | N-[(4-fluorophenyl)methylideneamino]-6-methoxy-2-methyl-quinolin-4-amine | N-[(4-fluorophenyl)methylideneamino]-6-methoxy-2-methylquinolin-4-amine | SMR000517671 | [(4-fluorobenzylidene)amino]-(6-methoxy-2-methyl-4-quinolyl)amine | [(E)-(4-fluorobenzylidene)amino]-(6-methoxy-2-methyl-4-quinolyl)amine | cid_3141521
TypeSmall organic molecule
Emp. Form.C18H16FN3O
Mol. Mass.309.3375
SMILESCOc1ccc2nc(C)cc(N=NCc3ccc(F)cc3)c2c1 |w:11.10|
Structure
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