| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83468 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83468 |
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| n/a |
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| Name | BDBM83468 |
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| Synonyms: | 2-[2-(4-Oxo-1-phenyl-1,4-dihydro-pyrazolo[3,4-d]pyrimidin-5-yl)-acetylamino]-benzoic acid methyl ester | 2-[[1-oxo-2-(4-oxo-1-phenyl-5-pyrazolo[3,4-d]pyrimidinyl)ethyl]amino]benzoic acid methyl ester | 2-[[2-(4-keto-1-phenyl-pyrazolo[3,4-d]pyrimidin-5-yl)acetyl]amino]benzoic acid methyl ester | MLS000034447 | SMR000007852 | cid_650943 | methyl 2-[2-(4-oxidanylidene-1-phenyl-pyrazolo[3,4-d]pyrimidin-5-yl)ethanoylamino]benzoate | methyl 2-[[2-(4-oxo-1-phenylpyrazolo[3,4-d]pyrimidin-5-yl)acetyl]amino]benzoate |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17N5O4 |
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| Mol. Mass. | 403.3908 |
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| SMILES | COC(=O)c1ccccc1NC(=O)Cn1cnc2n(ncc2c1=O)-c1ccccc1 |
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| Structure | 
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