Reaction Details |
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Target | Endoribonuclease toxin MazF |
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Ligand | BDBM39430 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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EC50 | >99000±n/a nM |
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Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Endoribonuclease toxin MazF |
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Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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BDBM39430 |
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n/a |
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Name | BDBM39430 |
Synonyms: | (3-Cyano-7-methyl-quinolin-2-ylsulfanyl)-acetic acid methyl ester | 2-[(3-cyano-7-methyl-2-quinolinyl)thio]acetic acid methyl ester | 2-[(3-cyano-7-methyl-2-quinolyl)thio]acetic acid methyl ester | MLS000072526 | SMR000001652 | cid_654307 | methyl 2-(3-cyano-7-methyl-quinolin-2-yl)sulfanylethanoate | methyl 2-(3-cyano-7-methylquinolin-2-yl)sulfanylacetate |
Type | Small organic molecule |
Emp. Form. | C14H12N2O2S |
Mol. Mass. | 272.322 |
SMILES | COC(=O)CSc1nc2cc(C)ccc2cc1C#N |
Structure |
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