Reaction Details |
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Target | Endoribonuclease toxin MazF |
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Ligand | BDBM83470 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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EC50 | 30300±n/a nM |
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Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Endoribonuclease toxin MazF |
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Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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BDBM83470 |
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n/a |
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Name | BDBM83470 |
Synonyms: | (3-morpholino-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-ylidene)amine;hydrochloride | 3-(4-morpholinyl)-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine;hydrochloride | 3-MORPHOLINOSYDNONIMINE | 3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine;hydrochloride | MLS000028691 | SMR000058925 | cid_9859122 |
Type | Small organic molecule |
Emp. Form. | C6H10N4O2 |
Mol. Mass. | 170.1692 |
SMILES | [NH-]c1c[n+](no1)N1CCOCC1 |
Structure |
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