| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83471 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | 9990±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83471 |
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| n/a |
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| Name | BDBM83471 |
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| Synonyms: | 2-cyano-N-[(4-methoxyphenyl)methyl]-2-(3-pyrrolidin-1-ylquinoxalin-2-yl)acetamide | 2-cyano-N-[(4-methoxyphenyl)methyl]-2-(3-pyrrolidin-1-ylquinoxalin-2-yl)ethanamide | 2-cyano-N-[(4-methoxyphenyl)methyl]-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetamide | 2-cyano-N-p-anisyl-2-(3-pyrrolidinoquinoxalin-2-yl)acetamide | MLS000079931 | SMR000040635 | cid_659705 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H23N5O2 |
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| Mol. Mass. | 401.461 |
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| SMILES | COc1ccc(CNC(=O)C(C#N)c2nc3ccccc3nc2N2CCCC2)cc1 |
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| Structure | 
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